canSERV open call for free state of the art services

13. 10. 2023 Call News Service

canSERV invites applications covering the entire range of the oncology developmental pipeline; supporting discoveries in fundamental research to translational science and personalised oncology.  canSERV welcomes excellent research applications addressing at least one of the four strategic goals of the Cancer Mission.  CCP provides following services under this call: Generation of precision cancer mouse models using…

New Czech laboratory for research on lethal viruses

10. 03. 2023 Information News Service

The new state-of-the-art BSL-3 laboratory for work with highly infectious viruses and bacteria in the Czech Republic was opened on 9 March at the Czech Centre for Phenogenomics (Institute of Molecular Genetics of the Czech Academy of Sciences in the BIOCEV centre). When it is fully operational, it will raise the level of Czech research…

CCP preclinical services in a nutshell

02. 02. 2023 Information News Service

Are you interested in our preclinical services? Download our latest leaflet with an overview of services we provide to our users in the area of preclinical services.

Isoplexis IsoLight Automated Celluar Proteomic in CCP

08. 08. 2022 Information News PR Service

We would like to inform our users that CCP now offers automated single cell functional proteomics analysis on the Isoplexis platform enabling for single cell functional immunophenotyping or phospho-protein analysis. If you want to know more about the device and services available in CCP for your research please check the details at our immunology unit…

AV21 Centre for Preclinical Testing: The path form the test tube to the patients

15. 07. 2022 Information News PR Service

To test substances that have succeeded in basic research and help them on the long journey from the test tube to the development of new drugs. This is the goal of the Centre for Preclinical Testing, funded by the Strategy of the Czech Academy of Sciences AV21. The centre is run in close collaboration of…

First call to access the ISIDORe resources dedicated to SARS-CoV-2 and COVID-19

10. 06. 2022 Call News Service

The first call is divided into six main sections which are: Surveillance & Epidemic Risk Management; Understanding SARS-CoV-2 & Covid-19; Diagnostics; Therapeutics; Vaccines; and Social Sciences & Epidemiology. The call is multidisciplinary and open to all scientists both from academia and private sector, including the partners of the ISIDORe consortium. The users wishing to benefit…

Preclinical testing of venom-derived compounds – open call for services

02. 05. 2022 Call Service

In the framework of the EUVEN COST Action the unique phenotyping infrastructure Czech Centre for Phenogenomics (CCP) will support researchers in searching for the novel utilization of venom-derived compounds and identifying their translational potential and identifying physiological functions of toxin compounds. CCP offers the following services free of charge within this open call: Acute toxicity…

Covid-19 mouse models available at CCP

02. 09. 2021 News Service

Ace2 knock-out model A number of promising COVID-19 therapies is focused on targeting the Ace2 receptor. Thus, it is desired to evaluate: the potential of Ace2 blocking to prevent viral entry into the cells unwanted off-target effects caused by Ace2 deficiency. Ace2 deficient mutant mice provide an excellent tool for these types of experiments. Tmprss2…

CCP provides services under Infrafrontier COVID-19 Open Call

19. 05. 2021 Call Service

In December 2020, Infrafrontier launched an attractive free-of-charge service for the biomedical research community fighting against the COVID-19 pandemic. The Infrafrontier call turned out to be the most successful open call of the consortium so far. 21 scientific institutions from eight countries applied to be one of the five research projects that an INFRAFRONTIER expert…

EuroPDX and PDXNet consortia publish a milestone paper on PDX reliability

12. 02. 2021 Information News Service

Woo, X.Y., Giordano, J., Srivastava, A. et al. Conservation of copy number profiles during engraftment and passaging of patient-derived cancer xenografts. Nat Genet 53, 86–99 (2021). Patient-derived xenografts (PDXs) are resected human tumors engrafted into mice for preclinical studies and therapeutic testing. It has been proposed that the mouse host affects tumor evolution during PDX engraftment and propagation, affecting…