New Advanced Methodologies

The newly established Advanced In Vitro Models (AIM) module is dedicated to developing and providing human cell-based alternatives and complements to animal models. AIM represents a critical strategic investment that elevates CCP from a rodent-centric infrastructure to a next-generation facility combining in vivo and in vitro approaches. More info

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AIM intends to provide a comprehensive range of in vitro cellular systems, including human induced pluripotent stem cells (iPSCs) and iPSC-derived 2D and 3D models, as well as mouse primary cell cultures, for modelling physiological and disease processes in controlled experimental environments. Currently the unit focuses on skin and neural cell types. As it expands, additional tissue-specific human and mouse models will be introduced to broaden its capabilities and service portfolio.

AIM directly supports global 3Rs imperatives (Replacement, Reduction, Refinement) and EU/US regulatory trends. AIM is not intended to replace rodent models — it is a complementary, human-relevant addition to CCP’s integrated preclinical pipeline: iPSC / organoid data → rodent genetic models → large-animal platforms.