We are enhancing our
understanding
of the genetic basis for
human diseases

What can we help you with

Microinjection

Model Generation

Genetically modified rodent models have become a key tool in basic and biomedical research. The ability to engineer the mouse genome has greatly transformed biomedical research in the last decade. 
Phenotyping

Phenotyping

The genomes of humans, mice and other species have been completely sequenced, yet the knowledge of genome sequences as such does not shed light on questions concerning the functions of these sequences. 

Animal Facility

The Animal Facility Module of the Czech Center for Phenogenomics is based on the latest advances in housing, breeding and care of laboratory mice and rats. 
Mouse tumors

Preclinical Testing

The Czech Centre for Phenogenomics can offer a very broad portfolio of highly standardized assays useful for preclinical studies on rodents including established disease models. 

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Latest News

23. 11. 2020

Read our new issue of the Phenogenomics Newsletter

The first issue of Volume 5 (2020) of the Phenogenomics Newsletter has been just released. It features overviews of the services available to researchers and current or potential collaboration partners. Its objective is to highlight recent achievements, introduce new technologies and directions for future development, and allows insights into work and life at the CCP.…

02. 11. 2020

Orbis Pictus Award 2020 to Elizabeth Hillman

The Orbis Pictus 2020 Award, sponsored by the Czech Centre for Phenogenomics, was awarded to Elizabeth M. C. Hillman, one of the most outstanding investigators in the fields of biophotonics and bioengineering. The Orbis Pictus Lecture was presented on the occasion of the 16th Transgenic Technology Meeting (TT2020). Elizabeth M.C. Hillman is a Professor of…

07. 10. 2020

Nobel Prize in Chemistry 2020 – CRISPR/Cas9 genetic scissors

The Nobel Prize in Chemistry 2020 was awarded jointly to Emmanuelle Charpentier and Jennifer A. Doudna for the development of a method for genome editing. For more information visit the Nobel Prize website. Interested in using CRISPR/Cas9 technology? Our proficient team of Transgenic and Archiving Module provides services from design to delivery of a mutant…

About Czech Centre for Phenogenomics

Genetically modified mouse models have become a key tool in basic and biomedical research. The ability to engineer the mouse genome has greatly transformed biomedical research in the last decade. Crucial for this technology is the ability to control the expression of genes of interest. It is possible to increase or decrease gene expression, or eliminate the expression of a gene completely.

Transgenic and gene knockout/knockin technologies have become important experimental tools for assigning functions to genes at the level of whole complexity of organism, creating models of genetic disorders, evaluating effects drugs and toxins, thus helping to answer fundamental issues in basic and applied research.