We are enhancing our
understanding
of the genetic basis for
human diseases

What can we help you with

Microinjection

Model Generation

Genetically modified rodent models have become a key tool in basic and biomedical research. The ability to engineer the mouse genome has greatly transformed biomedical research in the last decade. 
Phenotyping

Phenotyping

The genomes of humans, mice and other species have been completely sequenced, yet the knowledge of genome sequences as such does not shed light on questions concerning the functions of these sequences. 

Animal Facility

The Animal Facility Module of the Czech Center for Phenogenomics is based on the latest advances in housing, breeding and care of laboratory mice and rats. 
Mouse tumors

Preclinical Testing

The Czech Centre for Phenogenomics can offer a very broad portfolio of highly standardized assays useful for preclinical studies on rodents including established disease models. 

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Latest News

08. 08. 2022

Isoplexis IsoLight Automated Celluar Proteomic in CCP

We would like to inform our users that CCP now offers automated single cell functional proteomics analysis on the Isoplexis platform enabling for single cell functional immunophenotyping or phospho-protein analysis. If you want to know more about the device and services available in CCP for your research please check the details at our immunology unit…

25. 07. 2022

We are searching new colleagues!

A new positions of a PDX Model / Veterinary Specialist(s) and Histology Lab Technician are available in the CCP. For more details go to our Career page.

22. 07. 2022

A delegation of EU member states, representatives of the Council of the EU and the Ministry of Education,Youth and Sports visited the research infrastructures at the BIOCEV center

On July 21, 2022, a delegation of representatives of the Council of the EU and the Ministry of Education, Youth and Sports visited the BIOCEV, a joint centre of the Czech Academy of Sciences and Charles University in Vestec near Prague. The goal was to present large research infrastructures and their potential for collaboration in…

About Czech Centre for Phenogenomics

Genetically modified mouse models have become a key tool in basic and biomedical research. The ability to engineer the mouse genome has greatly transformed biomedical research in the last decade. Crucial for this technology is the ability to control the expression of genes of interest. It is possible to increase or decrease gene expression, or eliminate the expression of a gene completely.

Transgenic and gene knockout/knockin technologies have become important experimental tools for assigning functions to genes at the level of whole complexity of organism, creating models of genetic disorders, evaluating effects drugs and toxins, thus helping to answer fundamental issues in basic and applied research.