With staff over 100 people the CCP is one of the largest Czech research infrastructures in the field of biomedicine. Set on the campus of the BIOCEV in the municipality of Vestec south of the capital city of Prague, the CCP is a state of the art facility combining the generation, phenotyping and archiving of rodent strains. As a member of the International Mouse Phenotyping Consortium (IMPC) and INFRAFRONTIER, CCP is dedicated to the goal of systematic genome-wide phenotyping project of knock-out mice in order to provide the broader research community with a lasting resource of mammalian gene function
The CCP is part of the Institute of Molecular Genetics of the Czech Academy of Sciences (IMG), a leading Czech research institute in the field of molecular biology and genetics.
The applications in English including letter of interest & structured CV and (if relevant) a list of publications and letters of reference should be sent to Mr. Libor Daněk via email firstname.lastname@example.org.
What we offer to our employees?
You will join a stimulating and challenging work environment within the international team of dedicated researchers working with state-of-the-art equipment and instruments. We offer various opportunities for career advancement, a competitive salary and a wide spectrum of benefits.
The positions are available immediately (if not stated otherwise) for an initial fixed-term contract (1 year) with an expected longer-term extension upon demonstrated proficiency.
We thank all who apply for their interest; however, only those candidates who are considered for an interview will be contacted.
All positions have place of work in the BIOCEV campus in Vestec in close vicinity to Prague.
Currently we are seeking candidates to following positions:
Unit Head for Cardiovascular & Lung Function Phenotyping
The cardiovascular and lung function units are part of standardized phenotyping pipeline of the Czech Centre for Phenogenomics, which is involved in IMPC phenotyping effort.
The cardiovascular unit provides services to assess cardiovascular function in mouse and rat models. To perform rapid and in-depth analysis of the mouse or rat heart and circulatory system in both normal and disease states, we employed several state-of-art instrumentation that allows for sensitive screening of phenotypic variations. The lung function unit focuses on understanding the role of both genetic, environmental and pharmacological factors on lung physiology, homeostasis and mechanics.
The main responsibilities of the Unit Head include but are not limited to:
- Organization and supervision of the unit including management of lab technicians or research assistants
- Designing and running of experiments using ultrasound (vevo 2100 & 3100), EKG (ECGenine) and blood pressure (Kent Coda) monitoring stations
- Design and running of experiments including direct ventilation with Scireq devices with standard and advance measurements of lung mechanics parameters, tissue collection and immunological analysis of lung disease models
- Data analysis and interpretation
- Consulting of project proposal for CCP users
- Oversee the optimization of current procedures and development and establishment of new techniques, secondary tests and challenges
- Writing and maintaining SOPs
- Supervision and consulting of complex projects related to lung and cardiovascular system
- Involvement in writing grant applications and in publications
- (Future) possibility to run own research projects or supervising of students
The successful candidate will hold a PhD in a biological discipline with proved experience in cardiovascular or lung physiology. Must have experience with handling and working with rodents especially mice and rats. Previous experience with ultrasound imaging (Vevo system) or Scireq devices is considered advantageous as well as experience with pharmacological treatment of lung disease models.
We expect initial two-years contract with extension upon demonstrated proficiency. Starting date is negotiable.