VACANCY – Postdoc/junior researcher focused on Prader-Willi syndrome research and therapy development

Czech Centre for Phenogenomics (CCP) Institute of Molecular Genetics of the Czech Academy of Sciences, v. v. i. announces an open position for a “postdoc/junior researcher“ focused on Prader-Willi syndrome research and therapy development

The Czech Centre for Phenogenomics at the Institue of Molecular Genetics (Prague, CZ) is seeking a motivated and responsible candidate for the Postdoc position in the Phenotyping Module team, which develops and characterizes models of human genetic diseases.

 Work description and responsibilities:

  • Preclinical research of Prader-Willi syndrome in tight connection with a patient foundation
  • Molecular biology and cell culture (iPSC) work
  • Mouse model phenotyping analysis incl. behavioral and metabolism tests
  • Development of therapeutic AAV vectors, delivery studies
  • Efficacy studies of small molecule drugs
  • Taking a leading role towards the development of a subset of projects; working towards agreed deadlines, identifying and troubleshooting of risks at each step, seeking support when required.

Required skills/qualification:

  • PhD or equivalent in a biological subject or related field
  • Experience in a relevant position, particularly in molecular biology epigenetics, neurobiology,  metabolism and mammalian cell culture
  • Experience with mouse models (breeding, genotyping, colony maintenance)
  • Experience with in vivo phenotype analysis, metabolic testing is of advantage
  • Ability to work independently, lead and supervise students
  • Proficiency in English

We offer an extendable contract with a competitive salary scale based on performance. CCP, the top Czech science center, is located in a modern research building offering superb research facilities, international and enthusiastic working environment with opportunities to bring own ideas into practice and create own research projects. There are possibilities for professional growth and further education. Medical and social benefits included. Flexible working hours.

Contract details:

  • Full-time position; the selected candidate will be offered a one-year contract as a starting arrangement with potential for long-term extension based on demonstrated ability
  • Flexible start date
  • Workplace: CCP building at BIOCEV campus, Vestec (near Prague)

The application and CV should be sent to Ms Jana Safrankova ( If you have any further questions regarding the position, please send a message to this email.