Transgenesis & Wnt meeting in Telč

21. 05. 2014 Event Lecture

Scientific meeting “Gene targeting, genome editing & transgenesis: research application”

We are organizing joint meeting with our colleagues from Masaryk University in Brno dedicated to current progress in transgenic technologies in research application, animal models of diseases and Wnt signalling. The event is part of lecture series under the OP EC project reg. no. CZ.1.07/2.3.00/30.0027 “Founding the Centre of Transgenic Technologies“.

The event venue is hotel Anton in Telč. If you are willing to participate feel free to contact us at e-mail

Preliminary program of the event

Wednesday, 11 June 2014
17.00 arrival and registration
18.30 dinner
19.30 Welcome addresses by organizers
19.40 keynote lecture by Dalibor Blažek
Cyclins targeted: Transcriptional Cdks in human disease

Thursday, 12 June 2014
Transgenic technologies session
Chair Radislav Sedlacek

9.00 Dominika Fricova
Tools for gene targeting and genome editing
9.30 Slavomir Kinský
Talens and CRISPR/Cas9 – Efficient genome surgery tools
10.00 Irena Barnetova
Embryonic stem cell technologies & IKMC, IMPC, INFRAFRONTIER consortia
10.30 coffee break
11.00 Zuzana Ileninova
The Czech Centre for Phenogenomics: service offer
11.30 Miluse Hroudova
Next generation sequencing: designing experiment in transgenic animal research
12.30 lunch and afternoon break

Transgenic models session
Chairs V.Korinek & Z. Kozmik
16.00 Bohumil Fafílek
Cell tracking and manipulation in genetically modified mice
16.30 Michaela Krausová
Mouse transgenic model to study tumor progression and metastasis in the gut
17.00 coffee break
17.20 Matej Durik
Rodent transgenic models of cardiovascular diseases
17.50 Jan Masek
The role of Wnt/beta-catenin signaling in neural crest development: an insight from transgenic and knockout mice
19.00 dinner

Friday, 13 June 2014
Transgenic & gene manipulation: applications in Wnt signalling session
Chair V. Bryja

8.30 Hana Paculová
CDK12 connects transcriptional regulation to DNA damage repair pathway
8.55 Karol Kaiser
Wnt secretion during nervous system development
9.20 Simona Hankeová
The role of Notch signaling in vasculogenesis
10.00 Coffee break
10.30 Tomáš Doležal
Extracellular adenosine regulates complex host-pathogen interactions through the energy release for the immune response
10.55 Ondřej Bernatík and Igor Červenka
Regulation of diverse function of Dvl by phosphorylation
11.20 Jan Ryneš
Dissection of Axin interactome: rational approach for control of signaling cascades via intervention with specific protein-protein interactions
12.05 Targeting opportunities: discussion & sum-up
13.00 Lunch and departure