G3 symposium 2013 (Genes, Genetics & Genomics)

07. 02. 2013 Event Information

First Faculty of Medicine of the Charles University in Prague and Institute of Molecular Genetics of the ASCR will organising one-day symposium dedicated to recent discoveries on physiological as well as pathological cellular and molecular processes. The event will take place at IMG on March 15, 2013. More information and program updates are available at symposium web page.

G3 symposium web page link

Preliminary program:

Part I (9.30 a.m.-12 a.m., each talk will be 30 min including discussion)
Dr. Radek Sedlacek (chair of the session, Institute of Molecular Genetics, ASCR Prague): “The Czech Centre for Phenogenomics and Functional Genomics in BIOCEV”
Dr. Ralf Kühn (Helmholtz Zentrum, München, Germany): “Direct Production of Mouse Disease Models by Embryo Microinjection of TALENs and Oligodeoxynucleotides”
Dr. John Brognard (Paterson Institute for Cancer Research, The University of Manchester, UK): “Utilising Genetic Dependency Screens to Identify Mutationally Activated Drivers of Lung Cancer”
Dr. Libor Macurek (Institute of Molecular Genetics, ASCR Prague): “Role of PPM1D/Wip1 mutations in DNA damage signaling and cancer development”
Dr. Meritxell Alberich Jorda (Institute of Molecular Genetics, ASCR Prague): “The interplay between C/EBPa and C/EBPg in acute myeloid leukemia”

12 a.m. – 1 p.m. time for lunch

Part II (1 p.m.- 3 p.m., each talk will be 30 min including discussion)
Dr. Philipp Greif (Helmholtz Zentrum, München, Germany): “Exome Sequencing Identifies Cooperating Transcription Factor Mutations in Acute Myeloid Leukemia (AML): Simultaneous Targeting of GATA2 and CEBPA”
Dr. Tomas Stopka (chair of the session, Pathophysiology & BIOCEV, First Faculty of Medicine, Charles University in Prague): “Regulation of PU.1 gene transcription in MDS and AML.”
Dr. Peter Laslo (Leeds Institute of Molecular Medicine, University of Leeds, Leeds, UK): “Epigenetic regulation of the myeloid gene network by the BCR-ABL oncogene”
Dr. John Strouboulis (Institute of Molecular Oncology, BSRC Alexander Fleming, Varkiza, Greece): “GATA-1 regulatory networks in erythroid cells.”