Surgery

The Surgery Unit provides a centralized platform for standardized and advanced in vivo surgical procedures supporting phenotyping, disease modelling, and preclinical research. By combining high technical expertise with controlled and reproducible workflows, the Unit enables precise experimental interventions across multiple organ systems. The platform serves as a key integrative component of CCP pipelines, ensuring consistency, quality, and translational relevance of surgical procedures. More info
Head of Unit: Václav Žatečka
Research fellow:
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Centralization of surgical procedures ensures consistency, reduces variability between studies, and increases reproducibility across CCP pipelines. Unit performs a wide range of microsurgical and interventional procedures, including organ-specific delivery, vascular access, transplantation, and implantation of monitoring and dosing systems such as telemetric devices and osmotic pumps for continuous compound administration. Standardized protocols ensure high reproducibility and seamless compatibility with downstream phenotyping and analytical pipelines. Close integration with physiological, metabolic, imaging, and pathology units enables complex experimental designs, including longitudinal and recovery-based studies requiring precise and controlled in vivo interventions.

Standard services Reproductive and Endocrine Surgery

  • Ovariectomy
  • Vasectomy
  • Ovary transplantation

Standard services Vascular and Targeted Delivery Procedures

  • Catheter implantation (drug delivery, blood sampling)
  • Intra-arterial delivery (e.g. renal artery)
  • Intracavitary / organ-specific administration

Standard services Organ Transplantation and Tissue Engraftment

  • Renal capsule transplantation
  • Orthotopic tissue implantation

Standard services Implantation and Monitoring Systems

  • Telemetric device implantation
  • Catheter systems
  • Osmotic pump implantation (subcutaneous and intraperitoneal) for continuous drug delivery
  • Long-term physiological monitoring setups

Standard services Resection and Injury Models

  • Partial hepatectomy
  • Organ injury models (expandable later)