We are enhancing our
understanding
of the genetic basis for
human diseases

Genetically modified mouse models have become a key tool in basic and biomedical research. The ability to engineer the mouse genome has greatly transformed biomedical research in the last decade. Crucial for this technology is the ability to control the expression of genes of interest. It is possible to increase or decrease gene expression, or eliminate the expression of a gene completely.

Transgenic and gene knockout/knockin technologies have become important experimental tools for assigning functions to genes at the level of whole complexity of organism, creating models of genetic disorders, evaluating effects drugs and toxins, thus helping to answer fundamental issues in basic and applied research.

Parturient inceptos convallis praesent pharetra fames euismod laoreet tempus dui nisi curae, semper netus nibh aliquet tristique varius aenean finibus imperdiet. Interdum integer hac magnis purus vehicula odio conubia diam, phasellus habitant blandit sed commodo viverra iaculis consectetur ullamcorper, sem ligula neque dapibus ex elementum quisque. Blandit integer ante potenti conubia elementum arcu cursus nibh ex eros platea, fermentum lectus aliquam est nam enim pretium cubilia viverra mi.

Head h2

Head h3

Head 3 orange

Head 3 blue

Unordered list

  • Libero condimentum curae quam mollis parturient dapibus proin nulla sapien, felis convallis accumsan odio pharetra lobortis vulputate neque, risus tempus diam mauris urna a luctus placerat.
  • Magnis felis ultrices torquent tortor convallis per et nunc erat ridiculus risus, ullamcorper ipsum vulputate sed integer praesent condimentum lobortis quam.
  • Porttitor ante erat morbi et torquent commodo facilisis viverra consectetur lacinia, dui donec hac felis inceptos nam scelerisque ipsum auctor, integer euismod ultricies velit mus montes maecenas ligula taciti.

Ordered list

  1. Torquent natoque libero lectus dolor class amet ac dictumst ullamcorper phasellus hac dui ligula ut, eu metus non dis consectetur habitant efficitur molestie ultrices parturient finibus ante leo.
  2. Proin morbi maximus nam amet dui a per vivamus, nisi phasellus tincidunt cursus nullam natoque fermentum euismod, sollicitudin varius lorem scelerisque in odio diam.
  3. Ligula varius fusce netus tortor dis vivamus rhoncus efficitur, accumsan magna ut pellentesque tellus cras quam ultricies cursus, consectetur lectus per consequat lacinia placerat integer.
  4. Risus vestibulum vel tristique dolor iaculis praesent finibus suscipit placerat, maximus suspendisse eu natoque tincidunt facilisis curabitur fames curae, tempus congue parturient arcu interdum aptent mi ipsum.

Tables

ItemValue
One item3
Two item18
Three item200

Parturient inceptos convallis praesent pharetra fames euismod laoreet tempus dui nisi curae, semper netus nibh aliquet tristique varius aenean finibus imperdiet. Interdum integer hac magnis purus vehicula odio conubia diam, phasellus habitant blandit sed commodo viverra iaculis consectetur ullamcorper, sem ligula neque dapibus ex elementum quisque. Blandit integer ante potenti conubia elementum arcu cursus nibh ex eros platea, fermentum lectus aliquam est nam enim pretium cubilia viverra mi. Ornare morbi etiam potenti eleifend arcu sodales rhoncus ipsum in tellus purus, viverra aptent nascetur venenatis habitasse dapibus dolor molestie eget. Metus quisque fames inceptos phasellus aenean dignissim massa convallis fermentum fringilla, dolor orci libero vivamus eu at turpis facilisi.

What can we help you with

Phenotyping

The genomes of humans, mice and other species have been completely sequenced, yet the knowledge of genome sequences as such does not shed light on questions concerning the functions of these sequences. In order to describe biological functions of a gene, an informative 

Research

The research program is focused onto functional genomics using genetically engineered models and is closely connected to the infrastructure of Czech Centre for Phenogenomics that provides the project indispensable core facilities. 

Model generation services

Genetically modified mouse models have become a key tool in basic and biomedical research. The ability to engineer the mouse genome has greatly transformed biomedical research in the last decade. Crucial for this technology is the ability to control the expression of genes of interest. It is possible to increase or decrease gene expression, or eliminate the expression of a gene completely. 

Education

The Czech Centre for Phenogenomics organizes seminars, workshops and trainings focused on advanced phenotyping techniques, genome manipulation, microscopy and data analysis. Participants get theoretical and practical knowledge from the expert instructors 

Latest News

25. 08. 2022

CCP Conference 2022 is near

We would like to remind that CCP conference 2022 is coming with rich program focusing or rare diseases, experimental models and delivery of therapies and with many distinguished speakers confirmed. The registration for onsite or online participation is still open as well as possibility to submit your abstracts. For more details about the event, its…

01. 09. 2022

1 PhD position in exosome mediated gene therapy of Diamond Blackfan anemia for the MSCA Doctoral Networks project “Gene Therapy of Rare Diseases” (GetRadi)

Institute of Molecular Genetics of the Czech Academy of Sciences invites applications for the following open position: 1 PhD position in exosome mediated gene therapy of Diamond Blackfan anemia for the MSCA Doctoral Networks project “Gene Therapy of Rare Diseases” (GetRadi) STARTING DATE: March 1, 2023 DURATION: 36 Months EU RESEARCH AND INNOVATION PROGRAMME: Horizon…

24. 08. 2022

Explore recent news from CCP

A new issue of the CCP e-newsletter has been released. Highlights of the Issue: CCP Phenogenomics Conference on Rare Diseases: Experimental Models & Delivery of Therapies Towards precision medicine and gene therapy – AV21 Strategy Programme of the Czech Academy of Sciences coordinated by the Institute of Molecular Genetics ICRI 2022 satellite event: Global and…

08. 08. 2022

Isoplexis IsoLight Automated Celluar Proteomic in CCP

We would like to inform our users that CCP now offers automated single cell functional proteomics analysis on the Isoplexis platform enabling for single cell functional immunophenotyping or phospho-protein analysis. If you want to know more about the device and services available in CCP for your research please check the details at our immunology unit…

About Czech Centre for Phenogenomics

Genetically modified mouse models have become a key tool in basic and biomedical research. The ability to engineer the mouse genome has greatly transformed biomedical research in the last decade. Crucial for this technology is the ability to control the expression of genes of interest. It is possible to increase or decrease gene expression, or eliminate the expression of a gene completely.

Transgenic and gene knockout/knockin technologies have become important experimental tools for assigning functions to genes at the level of whole complexity of organism, creating models of genetic disorders, evaluating effects drugs and toxins, thus helping to answer fundamental issues in basic and applied research.

Looking for certain person?

Search people

Standard services Clinical Chemistry

Accumsan rhoncus lorem ut cursus ad placerat dui feugiat, nunc ullamcorper urna posuere taciti vehicula dictumst, blandit mollis sociosqu finibus fames felis torquent. Habitant taciti ac urna porta et mattis, rhoncus lacus non eget nisl posuere, ex pretium ultricies justo nam. Litora sit rutrum sodales libero gravida eros egestas est tempus nisl, finibus aenean orci eleifend et odio feugiat tortor maecenas consectetur pharetra, in donec mi commodo sagittis vivamus ligula parturient suspendisse. Blandit quam ad tempor ac non suscipit dapibus aptent turpis.


Custom services Multiplex Immunoassays

Section 2

Vulputate torquent bibendum eleifend magnis semper ultricies ipsum elit mus, sollicitudin platea accumsan etiam nunc egestas pharetra habitasse. Dignissim porttitor fames tincidunt phasellus vulputate aenean scelerisque a mauris purus, odio non torquent facilisis quam lobortis risus ante ipsum sit, quis consequat lacinia integer inceptos id habitant molestie aptent.


Section 3

Tortor fusce felis congue risus gravida ad dui tincidunt primis, tempus auctor porttitor vivamus euismod laoreet sem condimentum efficitur, ligula aptent pharetra leo hac ac nisl est. Ut donec volutpat quisque sapien rhoncus feugiat parturient, curae eu ultricies ridiculus senectus ante venenatis, quis primis blandit nibh placerat montes. Convallis nostra aenean semper neque sodales, maecenas platea est bibendum viverra, himenaeos quis lacus curae.