understanding
of the genetic basis for
human diseases
Genetically modified mouse models have become a key tool in basic and biomedical research. The ability to engineer the mouse genome has greatly transformed biomedical research in the last decade. Crucial for this technology is the ability to control the expression of genes of interest. It is possible to increase or decrease gene expression, or eliminate the expression of a gene completely.
Transgenic and gene knockout/knockin technologies have become important experimental tools for assigning functions to genes at the level of whole complexity of organism, creating models of genetic disorders, evaluating effects drugs and toxins, thus helping to answer fundamental issues in basic and applied research.
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- Magnis felis ultrices torquent tortor convallis per et nunc erat ridiculus risus, ullamcorper ipsum vulputate sed integer praesent condimentum lobortis quam.
- Porttitor ante erat morbi et torquent commodo facilisis viverra consectetur lacinia, dui donec hac felis inceptos nam scelerisque ipsum auctor, integer euismod ultricies velit mus montes maecenas ligula taciti.
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- Proin morbi maximus nam amet dui a per vivamus, nisi phasellus tincidunt cursus nullam natoque fermentum euismod, sollicitudin varius lorem scelerisque in odio diam.
- Ligula varius fusce netus tortor dis vivamus rhoncus efficitur, accumsan magna ut pellentesque tellus cras quam ultricies cursus, consectetur lectus per consequat lacinia placerat integer.
- Risus vestibulum vel tristique dolor iaculis praesent finibus suscipit placerat, maximus suspendisse eu natoque tincidunt facilisis curabitur fames curae, tempus congue parturient arcu interdum aptent mi ipsum.
Tables
| Item | Value |
|---|---|
| One item | 3 |
| Two item | 18 |
| Three item | 200 |
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Radislav Sedláček in Press Club of Frekvence 1 Radio about genes and human diseases
The guest of the Press Club was our leading expert on genetically modified organisms Radislav Sedláček from the Czech Centre for Phenogenomics. The presenter Bára Nesvadbová also came across a possible leak of the SARS-CoV-2 virus from the laboratory. You can listen to the whole interview here (in Czech).
Meet the new deputy director of the Czech Centre for Phenogenomics
Interview with Jan Procházka Jan Procházka, PhD has been appointed as the new deputy director of the Czech Centre for Phenogenomics (CCP). Jan leads the Phenotyping Module aiming at standardized, systematic characterization of mouse models as well as preclinical research and development. During his three-year postdoctoral fellowship at University of California Jan worked on tissue…
Czech Centre for Phenogenomics in the 2023 Roadmap of Large Research Infrastructures
The Czech Centre for Phenogenomics is listed in the Roadmap of Large Research Infrastructures of Czech Republic for the years 2023 – 2026. The updated Roadmap was published by the Ministry of Education, Youth and Sports.
About Czech Centre for Phenogenomics
Genetically modified mouse models have become a key tool in basic and biomedical research. The ability to engineer the mouse genome has greatly transformed biomedical research in the last decade. Crucial for this technology is the ability to control the expression of genes of interest. It is possible to increase or decrease gene expression, or eliminate the expression of a gene completely.
Transgenic and gene knockout/knockin technologies have become important experimental tools for assigning functions to genes at the level of whole complexity of organism, creating models of genetic disorders, evaluating effects drugs and toxins, thus helping to answer fundamental issues in basic and applied research.
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