understanding
of the genetic basis for
human diseases
Genetically modified mouse models have become a key tool in basic and biomedical research. The ability to engineer the mouse genome has greatly transformed biomedical research in the last decade. Crucial for this technology is the ability to control the expression of genes of interest. It is possible to increase or decrease gene expression, or eliminate the expression of a gene completely.
Transgenic and gene knockout/knockin technologies have become important experimental tools for assigning functions to genes at the level of whole complexity of organism, creating models of genetic disorders, evaluating effects drugs and toxins, thus helping to answer fundamental issues in basic and applied research.
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Head h2
Head h3
Head 3 orange
Head 3 blue
Unordered list
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- Magnis felis ultrices torquent tortor convallis per et nunc erat ridiculus risus, ullamcorper ipsum vulputate sed integer praesent condimentum lobortis quam.
- Porttitor ante erat morbi et torquent commodo facilisis viverra consectetur lacinia, dui donec hac felis inceptos nam scelerisque ipsum auctor, integer euismod ultricies velit mus montes maecenas ligula taciti.
Ordered list
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- Proin morbi maximus nam amet dui a per vivamus, nisi phasellus tincidunt cursus nullam natoque fermentum euismod, sollicitudin varius lorem scelerisque in odio diam.
- Ligula varius fusce netus tortor dis vivamus rhoncus efficitur, accumsan magna ut pellentesque tellus cras quam ultricies cursus, consectetur lectus per consequat lacinia placerat integer.
- Risus vestibulum vel tristique dolor iaculis praesent finibus suscipit placerat, maximus suspendisse eu natoque tincidunt facilisis curabitur fames curae, tempus congue parturient arcu interdum aptent mi ipsum.
Tables
| Item | Value |
|---|---|
| One item | 3 |
| Two item | 18 |
| Three item | 200 |
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Registration and abstract submission for the 5th CCP Phenogenomics Conference has been opened
It is our great honour to invite you cordially to the 5th CCP Phenogenomics Conference, which will be held on 14 – 15 September 2023 in Prague & online. Similarly, to the last year, the conference is devoted to the topic of rare diseases & their therapies this year, with special focus on experimental models…
Why are mice so important in biomedical research?
As the most common research mammal in the world, mice are key to many aspects of biomedical research and, in turn, scientific and medical advancements. Without mice, we would lack a crucial understanding of major diseases, including cancer and genetic disorders like muscular dystrophy, which has led to lasting benefits for humans and animals alike.…
Students from Charles University at CCP
The Czech Centre for Phenogenomics organized a theoretical and practical seminar “Phenotyping technologies for working with mouse models” for first year students of the Faculty of Science of Charles University in April 2023. The students of the subject “Molecular and General Biology” met Jan Prochazka from Phenotyping Module, who gave a lecture on phenotyping of…
About Czech Centre for Phenogenomics
Genetically modified mouse models have become a key tool in basic and biomedical research. The ability to engineer the mouse genome has greatly transformed biomedical research in the last decade. Crucial for this technology is the ability to control the expression of genes of interest. It is possible to increase or decrease gene expression, or eliminate the expression of a gene completely.
Transgenic and gene knockout/knockin technologies have become important experimental tools for assigning functions to genes at the level of whole complexity of organism, creating models of genetic disorders, evaluating effects drugs and toxins, thus helping to answer fundamental issues in basic and applied research.
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