We are enhancing our
understanding
of the genetic basis for
human diseases

Genetically modified mouse models have become a key tool in basic and biomedical research. The ability to engineer the mouse genome has greatly transformed biomedical research in the last decade. Crucial for this technology is the ability to control the expression of genes of interest. It is possible to increase or decrease gene expression, or eliminate the expression of a gene completely.

Transgenic and gene knockout/knockin technologies have become important experimental tools for assigning functions to genes at the level of whole complexity of organism, creating models of genetic disorders, evaluating effects drugs and toxins, thus helping to answer fundamental issues in basic and applied research.

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  • Magnis felis ultrices torquent tortor convallis per et nunc erat ridiculus risus, ullamcorper ipsum vulputate sed integer praesent condimentum lobortis quam.
  • Porttitor ante erat morbi et torquent commodo facilisis viverra consectetur lacinia, dui donec hac felis inceptos nam scelerisque ipsum auctor, integer euismod ultricies velit mus montes maecenas ligula taciti.

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  3. Ligula varius fusce netus tortor dis vivamus rhoncus efficitur, accumsan magna ut pellentesque tellus cras quam ultricies cursus, consectetur lectus per consequat lacinia placerat integer.
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What can we help you with

Phenotyping

The genomes of humans, mice and other species have been completely sequenced, yet the knowledge of genome sequences as such does not shed light on questions concerning the functions of these sequences. In order to describe biological functions of a gene, an informative 

Research

The research program is focused onto functional genomics using genetically engineered models and is closely connected to the infrastructure of Czech Centre for Phenogenomics that provides the project indispensable core facilities. 

Model generation services

Genetically modified mouse models have become a key tool in basic and biomedical research. The ability to engineer the mouse genome has greatly transformed biomedical research in the last decade. Crucial for this technology is the ability to control the expression of genes of interest. It is possible to increase or decrease gene expression, or eliminate the expression of a gene completely. 

Education

The Czech Centre for Phenogenomics organizes seminars, workshops and trainings focused on advanced phenotyping techniques, genome manipulation, microscopy and data analysis. Participants get theoretical and practical knowledge from the expert instructors 

Latest News

25. 03. 2024

Upgrade of the large research infrastructure CCP III

The goal of the project (ID: CZ.02.01.01/00/23_015/0008189) is to modernize the large research infrastructure of the Czech Center for Phenogenomics with the aim of maintaining its competitiveness and expanding the portfolio of services. The project comprises of three key activities (KA): KA1 – Project management KA2 – Modernization and upgrade of large research infrastructure KA3…

21. 03. 2024

CCP succeeded in the EIC Transition call

Czech Centre for Phenogenomics (Institute of Molecular Genetics of the Czech Academy of Sciences), which is a partner in the project TREM2MEDS – Towards the clinical implementation of TREM2 microglia engineering for treating dementia, succeeded as the only applicant from the Czech Republic in the EIC Transitions call. TREM2MEDS (coordinator: Universita degli Studi di Padova, Italy)…

27. 02. 2024

Apply for CCP services: Generation of precision cancer mouse models using CRISPR-Cas9 and In-depth cancer-based phenotyping of cancer mouse models

Open Call for Transnational Service Provision under the canSERV Open Call The researchers are welcome to apply to a portfolio of services offered by canSERV to address the research needs of the entire oncology developmental pipeline. CCP offers following services in this call: For more information visit canSERV website. Submission Deadline: 21 May 2024, 2pm…

About Czech Centre for Phenogenomics

Genetically modified mouse models have become a key tool in basic and biomedical research. The ability to engineer the mouse genome has greatly transformed biomedical research in the last decade. Crucial for this technology is the ability to control the expression of genes of interest. It is possible to increase or decrease gene expression, or eliminate the expression of a gene completely.

Transgenic and gene knockout/knockin technologies have become important experimental tools for assigning functions to genes at the level of whole complexity of organism, creating models of genetic disorders, evaluating effects drugs and toxins, thus helping to answer fundamental issues in basic and applied research.

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Standard services Clinical Chemistry

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Custom services Multiplex Immunoassays

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