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This year, the Czech Centre for Phenogenomics celebrates ten years as a national and European hub for advanced disease modelling and phenotyping. Founded from a small transgenic unit at the Institute of Molecular Genetics, CCP evolved into one of Europe’s largest and most advanced infrastructures for phenogenomics. Today, CCP employs around 140–145 specialists and operates fully as a large research infrastructure hosted by the Czech Academy of Sciences. Read more

Over the past decade, the phenotyping at the Czech Centre for Phenogenomics (CCP) has undergone a profound transformation, mirroring the broader evolution of functional genomics. What began as the development of standardized phenotyping pipelines has evolved into a robust scientific ecosystem that bridges gene discovery, disease mechanisms, and preclinical translation. Read more

While individual rare diseases affect relatively small populations, their collective impact is profound, touching the lives of over 300 million people worldwide. Despite this massive burden, the vast majority of these conditions lack approved therapies. To address this critical gap, CCP has established the RD-Factory program designed to function as a comprehensive ecosystem for the functional analysis and treatment of rare genetic variants. Read more

Under the theme “For Users, With Users,” the conference reinforced CCP’s role not just as a service provider, but as a strategic hub for collaborative discovery. The 2025 edition was particularly notable for its strong focus on translational medicine, moving beyond basic understanding of gene function to the practical application of therapies for untreated conditions. Read more

Is your research topic related to rare diseases? Do you want to get more information on how experimental models can boost your research? Join us for the 6th CCP Phenogenomics Conference. Deadline for abstract submission is 27th August 2024, so do not miss the opportunity to share research outcomes with our community. Register at: https://www.ccp-conference.cz/registration-abstracts-submission/ Read more

Are you an expert in rare diseases or does someone close to you suffer from a rare disease?Register to our 6th CCP Phenogenomic Conference 2024, where we will present examples of good practice in collaboration between rare disease researchers and patient organisations in Session 7 “Rare diseases & bottom-up efforts to develop (gene) therapies” Registration… Read more

We are delighted to announce the keynote and invited speakers of the 6th CCP Phenogenomics Conference 2024: Keynote speakers: Invited speakers: Read more

Organised annually by the Czech Academy of Sciences since 2015, the Science Fair is one of the largest popular educational events in the Czech Republic. Over an exhibition area of over 8,000m², visitors can view over 100 exhibitions from more than 90 exhibitors. Among the exhibitors you find scientific institutions and educational, innovative and technological… Read more

The goal of the project (ID: CZ.02.01.01/00/23_015/0008189) is to modernize the large research infrastructure of the Czech Center for Phenogenomics with the aim of maintaining its competitiveness and expanding the portfolio of services. The project comprises of three key activities (KA): KA1 – Project management KA2 – Modernization and upgrade of large research infrastructure KA3… Read more

The Czech Centre for Phenogenomics receives funding from public providers, which allows CCP to offer state-of-the-art services and technologies to its users. Therefore, all the work performed at CCP should be acknowledged by users in their outputs (publications, presentations etc.). This acknowledgement provides an evidence of the impact of CCP on quality of research and… Read more