Second call for mouse production service

04. 12. 2013 Call Information

The EC FP7 funded INFRAFRONTIER-I3 project supports European customers with a free of charge mouse production service. A total of 30 KO mouse models will be produced by this service and will be made available to the wider community via EMMA.

The second call supporting the production of 10 KO models is now open

Application forms can be downloaded from

Send your proposal to by 31st December 2013

The service provided covers the production of a minimum of two heterozygous mice carrying the targeted gene allele of choice from the corresponding validated gene-targeted ES cell clone(s).

Costs: The access to the INFRAFRONTIER-I3 resources allocated to this work package is free of charge. The free of charge access will also include the shipment cost of the produced live mice to the customer’s facility (covering shipment cost of up to 800 Euros / shipment). The cost for ES cell purchase from a repository and / or for shipment of ES cells to the INFRAFRONTIER mouse production centers must be covered by the selected applicants.

Eligibility: Applications for the INFRAFRONTIER-I3 TA can be submitted from customers based in eligible countries, namely:

EU Member States: Austria (AT), Belgium (BE), Bulgaria (BG), Cyprus (CY), Czech Republic (CZ), Denmark (DK), Estonia (EE), Finland (FI), France (FR), Germany (DE), Greece (GR), Hungary (HU), Ireland (IE), Italy (IT), Latvia (LV), Lithuania (LT), Luxembourg (LU), Malta (MT), Netherlands (NL), Poland (PO), Portugal (PT), Romania (RO), Slovakia (SK), Slovenia (SI), Spain (ES), Sweden (SE), United Kingdom (GB).

Associated Countries: Albania (AL), Bosnia and Herzegovina (BA), Croatia (HR), Former Yugoslav Republic of Macedonia (MK), Faroe Islands (FO), Iceland (IS), Israel (IL), Liechtenstein (LI), Republic of Moldova (MD), Montenegro (ME), Norway (NO), Serbia (RS), Switzerland (CH), Turkey (TR).

Application: Service requests for the 2nd call of the INFRAFRONTIER-I3 mouse production service can be made via an application form that can be downloaded from Applications for the Transnational Access activity must be accompanied by a short description of the project involving the resources being produced by the INFRAFRONTIER-I3 mouse production service. Applications may be submitted in response to a total of 3 calls each providing 10 access units.

Selection procedure: Service requests from eligible customers for free of charge access to this INFRAFRONTIER-I3 TA service will be subject to a review procedure which will be initiated after calls for TA applications are closed. All applications will be treated with strict confidentiality. The review will be based on short descriptions of the projects involving the mouse mutants that are generated by the TA service. Members of the external INFRAFRONTIER Evaluation Committee will assess service requests supported by the TA activity. Selection criteria are 1) availability of ES cells, 2) scientific merit, 3) soundness of submitted proposal, and 4) access of applicants to transgenic facilities. The panel will ensure that free access is granted to those users who have not previously benefited from this scheme. IKMC ES cell clones that are assigned for mouse production in IMPC ( will not be con sidered by the panel. Only one access unit will be granted to a principal investigator per call. Applicants will be informed on the outcome of the evaluation within 4 weeks after the end of the call for which the TA application was submitted.