Nabídka pracovních pozic ve zvěřinci ÚMG níže na stránce.

With staff around 100 people the CCP is one of the largest national research infrastructures in the field of biomedicine. The center is located in the municipality of Vestec south of the capital city of Prague in the Czech Republic. Set on the campus of the BIOCEV, CCP is a state of the art facility combining the generation, phenotyping and archiving of rodent strains. As a member of the International Mouse Phenotyping Consortium (IMPC) and INFRAFRONTIER, CCP is dedicated to the goal of systematic genome-wide phenotyping project of knock-out mice in order to provide the broader research community with a lasting resource of mammalian gene function

The CCP is part of Institute of Molecular Genetics of the Academy of Sciences of the Czech Republic (IMG), leading Czech research institute in the field of molecular biology and genetics.

For further information please contact project coordinator Mr. Libor Daněk via email libor.danek@img.cas.cz.

The applications in English including letter of interest & structured CV and (if relevant) list of publications and letters of reference should be sent via above-mentioned email as well.

We offer a stimulating and challenging work environment, opportunities for career advancement, and competitive salary. The positions are available immediately (if not stated otherwise) for an initial fixed-term contract (1 year), with possible longer-term extension upon demonstrated proficiency.

We thank all who apply for their interest; however, only those candidates who are considered for an interview will be contacted. All vacancies are open until filled or otherwise stated.

All positions have place of work in BIOCEV campus in Vestec in close vicinity to Prague except otherwise stated.

Currently we are seeking candidates to following positions:

Open Position

Laboratory technician in molecular biology – genotyping

The Genotyping Unit of the Transgenic and Archiving Module of the CCP is currently seeking a motivated technician to join our international team. Your key responsibilities will be analysis of genetically modified mouse and rat models by different genotyping strategies, as well as general laboratory work incl. media preparation, cell culture and documentation of the work. As assistance for the Transgenic Unit animal handling will be as well part of the engagement.

You should possess a bachelor’s degree in biology, molecular biology, biotechnology or related subject. Experience in rodent handling as well as knowledge in rodent genetics and transgenic technologies would be advantageous as well as valid certificate for work with animals. Candidates should be able to communicate in English, have good interpersonal communication skills and be able to work independently as well as part of a team.

Open Position

PhD student position – Tiki, Wnt-specific Metalloproteases

For our research lab of the Laboratory of Transgenic Models of Diseases that is part of BIOCEV research program 1 we are looking for prospective student focused on elucidation of the biological role of Tiki, Wnt-specific Metalloproteases

Project description
The project focuses on TIKI1 and especially TIKI2 (TRABD2A and TRABD2B genes) whose biological role in mammals is still purely understood. TIKIs function as negative regulators of the Wnt signaling pathway, mediating cleavages of N-terminal residues of a subset of Wnt proteins. Phylogenetic analysis shows that Tiki1 and Tiki2 orthologues are highly conserved among vertebrate and mammalian species although the Tiki1 is missing in rodents. The role of Tiki proteases will be studied in mouse and human systems and the work will start with the analysis of our TIKI2 –deficient mice. The aim of this study is to describe the pathophysiologic roles of TIKI2 (TIKI1).

Candidate’s profile (requirements)
M.Sc. (Mgr.) degree or equivalent in molecular/cellular biology or biochemistry, a good command of English, independent thinking but also team player, strong interest in basic research and experimental work, ability to work with animals (rodents – training will be provided).

Open Position

Pathologist (rodent pathology)

To advance and further improve services of our histopathology lab we are seeking experienced pathologist who will be responsible for analyses and descriptions of mouse and rat tissue samples, especially:
– to provide expertise in the pathology of genetically-engineered mouse (GEM) and rat models
– to provide full pathology analysis including complete gross- and histopathological evaluation supplied with image-based report, digital images, and recommendations
– to perform phenotype investigation and characterization together with histology-lab managing scientist; this includes necropsy, macroimaging, tissue sample collection, supervision of histological processing, histopathological evaluation, digital photomicrographs, and consultations.
– to follow and implement GLP rules and manage work of lab technicians
– to drive his/her own research projects and actively participate within the other projects of the Centre.

Successful applicant should have DVM or MD (or equivalent advanced degree in relevant field) and relevant research and/or hands-on experience. Capability to work in English speaking environment is a must, previous experience with SOPs for GLP is an asset.

Open Position

IT Database Administrator / Data Specialist

We are seeking a qualified and motivated developer/IT specialist to adapt, manage, and further develop a LAMP-based database for phenotyping research results. The successful candidate will support the specific needs of the application, including data handling, scripting, creating templates, setting up workflows, fixing errors, educating users and co-develop the software. This database employs Perl and JSP with some additional R scripts.

Required Skills
– data handling – collecting, processing, analysis workflows
– development of web-based applications on LAMP
– proficiency in programming in at least one script language Perl/Python/PHP
– experience with JavaServer Pages (JSP) technology
– mySQL, postgreSQL administration
– solid English communication skills
– at least 3 years of LAMP experience is an advantage

We offer a competitive salary based on experience and track record and work in a new state-of-the-art centre with excellent collaboration conditions and an international working environment.

The position is available immediately as full time or part time depending on mutual agreement. The place of work is in BIOCEV / CCP in Vestec however remote access and work from home might be possible as well.

In addition to CV and motivation letter applications should include also references to finished databases, web or application projects in which the applicant participated and linkedin profile if available.

Open Position

Research position (postdoc) in ubiquitin ligases or molecular biology

A postdoctoral research scientist position is available immediately in the Laboratory of Transgenic Models of Diseases  the Institute of Molecular Genetics of the ASCR, v.v.i. located in BIOCEV (CCP building) We undertake various approaches to understand the function of several E3 ubiquitin ligases by using mouse models with their potential to be instrumental for the study of the disease mechanisms, particularly cancer and inflammatory diseases.

We are looking for a highly motivated individual with a strong background and skillset in biochemistry and molecular biology. You should have a PhD in biology or biochemistry and have a good proficiency in English. Experience in protein biochemistry is a plus. Your work will focus on wet bench projects including in vitro, in vivo, and mouse models with the goal of elucidating the molecular mechanisms of ubiquitination mediated by RING-type E3 ubiquitin ligases.

Interested candidates should provide motivation letter, CV and contacts to at least two independent professionals who can provide reference.


Jobs in Animal Facility / Zaměstnání ve zvěřinci ÚMG

For information regarding jobs in animal facility please contact Mrs Marketa Rynekrova at marketa.rynekrova@img.cas.cz or by phone at +420 241 063 182. For those positions application in Czech or Slovak or English language are accepted.

Pro informace o pracovních pozicích ve zvěřinci ÚMG prosím kontaktujte paní Markétu Rynekrovou na emailu marketa.rynekrova@img.cas.cz nebo telefonním čísle 241 063 182. Pro tyto pozice přijímáme žádosti o zaměstnání v českém, slovenském nebo anglickém jazyce.

Open Position

Technicians for animal facility / Technik nebo technička pro zvěřinec

Hlavní náplň práce:
– obsluha a údržba laboratorních technologií zvěřince (zejména systémy chovných nádob)
– obsluha mycích a dezinfekčních automatů spojená s jejich údržbou

Profil vhodného uchazeče:
– ukončené středoškolské vzdělání technického oboru
– osvědčení dle § 6 vyhlášky č. 50/1978 Sb. o odborné způsobilosti v elektrotechnice
– znalost anglického jazyka minimálně na úrovni porozumění technického textu, komunikační úroveň výhodou
– technická zručnost a orientace v technické dokumentaci (včetně anglicky psané)

Pracovní podmínky:
– pracoviště – Ústav molekulární genetiky AV ČR, Praha 4, nebo centrum BIOCEV ve Vestci u Prahy
– atraktivní práce na předním výzkumném pracovišti
– příplatek na stravování
– platové podmínky odpovídající dané pozici
– nástup dle dohody

Open Position

Animal caretakers / Ošetřovatele laboratorních zvířat

Hlavní náplň práce:
– zodpovědnost za péči o laboratorní zvířata
– sledování zdravotního stavu zvířat
– samostatné provádění odborných úkonů
– efektivní podpora vědeckým skupinám ústavu
– zadávání chovatelských dat do počítače

Profil vhodného uchazeče:
– absolvent střední veterinární školy nebo střední zemědělské školy nebo jiné vhodné vzdělání
– samostatnost
– přesnost, spolehlivost
– základní znalost práce s PC
– praxe v oboru výhodou, úspěšnému uchazeči bude poskytnuto doplňující školení

Pracovní podmínky:
– pracoviště – Ústav molekulární genetiky AV ČR, Praha 4, nebo centrum BIOCEV ve Vestci u Prahy
– atraktivní práce na předním výzkumném pracovišti
– příplatek na stravování
– platové podmínky odpovídající dané pozici
– nástup dle dohody