Information

On the occasion of the International Day of Rare Diseases Czech Centre for Phenogenomics in collaboration with BIOCEV and Czech Academy of Sciences issued a press release summarizing their research in the area of rare diseases. The press release (in English) is available on the BIOCEV website. The press release (in Czech) is available on… Read more

We are celebrating the International Angelman Day on 15th February. Angelman’s syndrome is an inherited disease of the central nervous system that causes severe physical and mental disabilities. The team of the Czech Center for Phenogenomics is engaged in research of Angelman’s syndrome (and other rare diseases) on mouse models created by us or already… Read more

Our collaboration with Luca Varani’s lab from the Institute for Research in Biomedicine in Bellinzona in Switzerland will expand thanks to the grants of the Czech and the Swiss Science Foundations. Both foundations decided to fund our joint project “SARS-Cov-2: understanding the entry, multi-organ spread and immune response in the context of vaccination and re-infection”… Read more

On Friday 21st January 2022, the Scientific Advisory Board met virtually and discussed with CCP management the achievements of 2021 and future directions of the Centre for the period 2022-2029. Besides the traditional reports about 2021 outcomes in research services, research and development of new methodologies, the presented highlights focused on: Cardiovascular comprehensive screening for… Read more

The first issue of our brand new online newsletter is available on https://phenogenomics.cz. We are delighted to share our recent achievements and updates on mouse phenogenomics, so from now on, the latest developments at CCP will be directly delivered to you via e-mail, with a dedicated website and interesting links for further reading. Enjoy reading… Read more

In the first half of 2021, the Ministry of Education, Youth and Sports organized an international peer-review of large research infrastructures in the Czech Republic, which results were published in December. The purpose of this evaluation was to obtain independent expert reviews about the performance of large research infrastructures. CCP confirmed its top level. According… Read more

The updated ESFRI Roadmap was published this week. INFRAFRONTIER is mentioned as an example of ESFRI Research Infrastructures in response to emergencies, specifically to the covid-19 crisis. “INFRAFRONTIER rapidly evolved a broad portfolio of services to evaluate the potential of new anti-COVID-19 compounds and therapeutics on suitable humanized models as well as BSL3 laboratories for… Read more

The Governor of the Central Bohemian Region Petra Pecková, Regional Council Member for the Environment Jana Skopalíková, and Regional Council Member for Health Pavel Pavlík visited the Czech Centre for Phenogenomics during their visit of BIOCEV, the joint research campus of the Czech Academy of Sciences and Charles University in Vestec near Prague, on 14th… Read more

The ESFRI announced the new three research infrastructures in the Health and Food domain to be included in the new ESFRI Roadmap 2021: EBRAINS (European Brain Research Infrastructures) is a distributed digital infrastructure at the interface of neuroscience, computing and technology, offering scientists and developers advanced tools and services for brain research. EIRENE (Research Infrastructure… Read more

Woo, X.Y., Giordano, J., Srivastava, A. et al. Conservation of copy number profiles during engraftment and passaging of patient-derived cancer xenografts. Nat Genet 53, 86–99 (2021). https://doi.org/10.1038/s41588-020-00750-6 Patient-derived xenografts (PDXs) are resected human tumors engrafted into mice for preclinical studies and therapeutic testing. It has been proposed that the mouse host affects tumor evolution during PDX engraftment and propagation, affecting… Read more