News

This year, the Czech Centre for Phenogenomics celebrates ten years as a national and European hub for advanced disease modelling and phenotyping. Founded from a small transgenic unit at the Institute of Molecular Genetics, CCP evolved into one of Europe’s largest and most advanced infrastructures for phenogenomics. Today, CCP employs around 140–145 specialists and operates fully as a large research infrastructure hosted by the Czech Academy of Sciences. Read more

Over the past decade, the phenotyping at the Czech Centre for Phenogenomics (CCP) has undergone a profound transformation, mirroring the broader evolution of functional genomics. What began as the development of standardized phenotyping pipelines has evolved into a robust scientific ecosystem that bridges gene discovery, disease mechanisms, and preclinical translation. Read more

While individual rare diseases affect relatively small populations, their collective impact is profound, touching the lives of over 300 million people worldwide. Despite this massive burden, the vast majority of these conditions lack approved therapies. To address this critical gap, CCP has established the RD-Factory program designed to function as a comprehensive ecosystem for the functional analysis and treatment of rare genetic variants. Read more

Under the theme “For Users, With Users,” the conference reinforced CCP’s role not just as a service provider, but as a strategic hub for collaborative discovery. The 2025 edition was particularly notable for its strong focus on translational medicine, moving beyond basic understanding of gene function to the practical application of therapies for untreated conditions. Read more

The Czech Centre for Phenogenomics (CCP) is excited to announce the 3rd Call for Nomination of Genes or Diseases within the RD-Factory program. This continuous call invites proposals from scientists, clinicians, patient groups, and affected families, aiming to: More information – Rare Disease Factory Read more

The program of conference TT2025 (https://tt2025.org/programme/) also included the presentation of the lecture award Orbis Pictus given by the Czech Centre for Phenogenomic. This year was awarded the lecture of Professor Anna-Katerina Hadjantonakis, Chair of Developmental Biology Program, Sloan Kettering Institute, New York, USA. Read more

CCP is happy to provide large porfolio of phenotyping and preclinical services to research community. Read more

Hope for patients affected by SPATA5 disease in CCP: https://archiv.hn.cz/c1-67711270-v-cesku-odstartoval-unikatni-vyzkum-vzacne-geneticke-poruchy-iniciovali-ho-rodice-deti-s-touto-diagnozou Read more

There is actually proceeding second round of nominations in RD-Factory program ending on 30th June 2025. Read more

There are thousands of rare diseases that are often insufficiently researched and for which there is no effective treatment. The Czech Centre for Phenogenomics (CCP), a large research infrastructure at the Institute of Molecular Genetics of the Czech Academy of Sciences, has therefore launched the RD-Factory program, which aims to find out more about these… Read more