We are enhancing our
understanding
of the genetic basis for
human diseases

What can we help you with

Microinjection

Model Generation

Genetically modified rodent models have become a key tool in basic and biomedical research. The ability to engineer the mouse genome has greatly transformed biomedical research in the last decade. 
Phenotyping

Phenotyping

The genomes of humans, mice and other species have been completely sequenced, yet the knowledge of genome sequences as such does not shed light on questions concerning the functions of these sequences. 

Animal Facility

The Animal Facility Module of the Czech Center for Phenogenomics is based on the latest advances in housing, breeding and care of laboratory mice and rats. 
Mouse tumors

Preclinical Testing

The Czech Centre for Phenogenomics can offer a very broad portfolio of highly standardized assays useful for preclinical studies on rodents including established disease models. 

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Latest News

19. 02. 2024

Updated acknowledgement of CCP in research outputs

The Czech Centre for Phenogenomics receives funding from public providers, which allows CCP to offer state-of-the-art services and technologies to its users. Therefore, all the work performed at CCP should be acknowledged by users in their outputs (publications, presentations etc.). This acknowledgement provides an evidence of the impact of CCP on quality of research and…

16. 02. 2024

ASGENT continues supporting CCP research on Angelman syndrome in 2024

On the occasion of the International Angelman Syndrome Day, Radislav Sedlacek, director of the Czech Centre fo Phenogenomics, received yesterday a cheque in the amount of CZK 1 million for the continuation of Angelman syndrome research using mouse models from the Association of Gene Therapy (ASGENT), which has long supported this research.At the same time,…

14. 02. 2024

Jobs available in CCP

HEAD OF CARDIOVASCULAR UNIT Successful candidate will be part of an international team with dedicated and professional attitude and has to fulfill the following requirements: Job description at the Cardiovascular Unit (https://www.phenogenomics.cz/phenotyping/cardiovascular/): Leading, Conducting ,and Supervising Experiments: Leading and overseeing cardiovascular experiments, ensuring high scientific standards and adherence to relevant protocols; ensurign collaboration with other…

About Czech Centre for Phenogenomics

Genetically modified mouse models have become a key tool in basic and biomedical research. The ability to engineer the mouse genome has greatly transformed biomedical research in the last decade. Crucial for this technology is the ability to control the expression of genes of interest. It is possible to increase or decrease gene expression, or eliminate the expression of a gene completely.

Transgenic and gene knockout/knockin technologies have become important experimental tools for assigning functions to genes at the level of whole complexity of organism, creating models of genetic disorders, evaluating effects drugs and toxins, thus helping to answer fundamental issues in basic and applied research.