We are enhancing our
understanding
of the genetic basis for
human diseases

What can we help you with

Microinjection

Model Generation

Genetically modified rodent models have become a key tool in basic and biomedical research. The ability to engineer the mouse genome has greatly transformed biomedical research in the last decade. 
Phenotyping

Phenotyping

The genomes of humans, mice and other species have been completely sequenced, yet the knowledge of genome sequences as such does not shed light on questions concerning the functions of these sequences. 

Animal Facility

The Animal Facility Module of the Czech Center for Phenogenomics is based on the latest advances in housing, breeding and care of laboratory mice and rats. 
Mouse tumors

Preclinical Testing

The Czech Centre for Phenogenomics can offer a very broad portfolio of highly standardized assays useful for preclinical studies on rodents including established disease models. 

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Latest News

31. 05. 2023

Registration and abstract submission for the 5th CCP Phenogenomics Conference has been opened

It is our great honour to invite you cordially to the 5th CCP Phenogenomics Conference, which will be held on 14 – 15 September 2023 in Prague & online. Similarly, to the last year, the conference is devoted to the topic of rare diseases & their therapies this year, with special focus on experimental models…

10. 05. 2023

Why are mice so important in biomedical research?

As the most common research mammal in the world, mice are key to many aspects of biomedical research and, in turn, scientific and medical advancements. Without mice, we would lack a crucial understanding of major diseases, including cancer and genetic disorders like muscular dystrophy, which has led to lasting benefits for humans and animals alike.…

21. 04. 2023

Students from Charles University at CCP

The Czech Centre for Phenogenomics organized a theoretical and practical seminar “Phenotyping technologies for working with mouse models” for first year students of the Faculty of Science of Charles University in April 2023. The students of the subject “Molecular and General Biology” met Jan Prochazka from Phenotyping Module, who gave a lecture on phenotyping of…

About Czech Centre for Phenogenomics

Genetically modified mouse models have become a key tool in basic and biomedical research. The ability to engineer the mouse genome has greatly transformed biomedical research in the last decade. Crucial for this technology is the ability to control the expression of genes of interest. It is possible to increase or decrease gene expression, or eliminate the expression of a gene completely.

Transgenic and gene knockout/knockin technologies have become important experimental tools for assigning functions to genes at the level of whole complexity of organism, creating models of genetic disorders, evaluating effects drugs and toxins, thus helping to answer fundamental issues in basic and applied research.