The genomes of humans, mice and other species have been completely sequenced, yet the knowledge of genome sequences as such does not shed light on questions concerning the functions of these sequences. In order to describe biological functions of a gene, an informative genetic modification are introduced into the genes. Mouse and rat are excellent models in search for gene functions.
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The research program is focused onto functional genomics using genetically engineered models and is closely connected to the infrastructure of Czech Centre for Phenogenomics that provides the project indispensable core facilities. The research groups have built up a substantial expertise and have already attained considerable scientific results in the field of functional genomics.
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Model generation services
Genetically modified mouse models have become a key tool in basic and biomedical research. The ability to engineer the mouse genome has greatly transformed biomedical research in the last decade. Crucial for this technology is the ability to control the expression of genes of interest. It is possible to increase or decrease gene expression, or eliminate the expression of a gene completely.
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The Czech Centre for Phenogenomics organizes seminars, workshops and trainings focused on advanced phenotyping techniques, genome manipulation, microscopy and data analysis. Participants get theoretical and practical knowledge from the expert instructors, have ample opportunity for discussion and can also bring their own data to work on during the bioinformatics session.
The Czech Centre for Phenogenomics (CCP) Institute of Molecular Genetics of the Czech Academy of …
3rd Programmable Nucleases (CRISPR/Cas9) Transgenesis Course Open lectures by our distinguished guest speakers in BIOCEV …
If you are looking for exciting work in analysis of large complex data sets and …
Czech Centre for Phenogenomics and company RMI s.r.o. would like to invite you to an …
The course is designed to give practical, hands-on training in current technologies and methods employing …
Workshop – New innovative technology in rodent body temperature telemetry Focus on brown fat metabolism …